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June 25, 2026· 4 min read

The Fresno Family That Says It Brought Botox to Town

Spotlight on Mystique Medical Spa & Wellness Center, Fresno. Part of a series profiling the people behind California med spas worth knowing about.

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A family business, literally

Mystique Medical Spa in Fresno is a Krikorian family business. S.S. Krikorian, DC, QME — a chiropractor and Qualified Medical Evaluator — founded it, and his daughter, Barbara Krikorian Tryk, is the COO. It is the opposite of a private-equity roll-up wearing a soft name.

By the practice's account, Mystique introduced Botox to Fresno. Whatever the precise history, the longevity is not in dispute: this is a Central Valley institution, not a pop-up.

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The receipts

One of its providers, Abby, FNP-C, holds certifications from Allergan Master Expert training and CoolSculpting University. The treatment menu is current — CoolSculpting Elite and CoolTone, DENSITY skin tightening, SKINVIVE, microneedling — but the reason to trust it is the decades behind it.

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Why it made the series

The aesthetics industry is consolidating, and a lot of the warmth is being optimized out of it. A family that has answered to the same city for decades has a kind of accountability no chain can buy: they cannot leave. If you are in the Valley, that is worth something — and it is worth reading their listing next to the rest.

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